Base on Mac OS X: I use Audacity for editing many mp3 file. To remove vocal sound, I will introduce you to use " Center Pan Remover ". or VoxReducer You just put it into plugin folder of Audacity program. If you cannot find plug-in folder, you can create it via 1. Access to Applications/Audacity 2. Create folder Plug in folder Reference: http://wiki.audacityteam.org/index.php?title=Vocal_Removal http://loudsoftware.com/?HG=Downloads